Learning outcomes of the course unit
The purpose of this course is to provide an in-depth background in histocompatibilty (MHC-HLA) applied to clinical transplantation.
Student must have basic knowledge in biology, immunology and genetics.
Course contents summary
Structure and biological role of MHC-HLA molecules. Genetics of HLA antigens in populations and families. Tissue typing methods (serology and molecular). HLA in clinical settings: tissue and organ transplantation. HLA compatibility and graft survival. Role of HLA sensisitization in kidney transplantation.
Browning M, McMichael A: HLA and MHC: Genes, Molecules and Function. BIOS Ed