MICROBIOLOGY
cod. 08708

Academic year 2007/08
3° year of course - First semester
Professor
Academic discipline
Microbiologia e microbiologia clinica (MED/07)
Field
Patologia generale e molecolare, immunologia, fisiopatologia generale e microbiologia
Type of training activity
Characterising
32 hours
of face-to-face activities
4 credits
hub:
course unit
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Learning objectives

Students have to know: <br />
1. the morphology and structure of bacteria/ fungi/ parasites/ viruses, the physiology of bacteria/ fungi/ parasites and the replication of viruses <br />
2. the classification of bacteria/ fungi/ parasites/ viruses <br />
3. the natural history of infections by bacteria/ fungi/ parasites/ viruses and their pathogenicity <br />
4. the main defense mechanisms of the host against infections by bacteria/ fungi/ parasites/ viruses <br />
5. the main activity mechanisms of drugs against bacteria/ fungi/ parasites/ viruses and the resistance mechanisms to drugs <br />
6. the laboratory procedures to study the morphology of bacteria/ fungi/ parasites/ viruses, to culture these agents and to investigate their antimicrobial in vitro susceptibility and the activity of antiviral agents. <br />

Prerequisites

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Course unit content

SYSTEMATIC BACTERIOLOGY <br />
Morphology, cultivation, identification, mechanisms of pathogenicity, natural history of infections with reference to the following bacteria: <br />
Staphylococcus (S. aureus, S. epidermidis, S. haemolyticus and other species); Streptococcus (S. pyogenes, S. agalactiae, S. pneumoniae); Enterococcus (S. faecalis, S. faecium and other species); Neisseria (N. meningitidis, N. gonorrhoeae); Salmonella and other main Enterobacteriaceae (Escherichia coli, Shigella, Edwardsiella, Citrobacter, Klebsiella, Enterobacter, Hafnia, Serratia, Proteus, Morganella, Providencia, Yersinia); Vibrio, Campylobacter; Brucella; Bordetella; Haemophilus; Corynebacterium diphtheriae; Listeria; Legionella; Pseudomonas, Acinetobacter; Mycobacterium, Nocardia, Rhodococcus; Bacillus anthracis. <br />
Anaerobic bacteria: Streptococcus/ Peptostreptococcus; Bacteroides, Porphyromonas, Prevotella, Fusobacterium; Clostridium (C. tetani, C. perfringens, C. difficile, C. botulinum); <br />
Gram-positive non sporeforming bacteria: (Lactobacillus, Bifidobacterium, Propionibacterium, Actinomyces (A. israeli and other species); Spirochetes (Treponema, Leptospira, Borrelia, Brachyspira); Mycoplasma; Chlamydia; Rickettsia. <br />
SYSTEMATIC MYCOLOGY <br />
Yeasts. Moulds. Etiologic agents of superficial mycoses. Etiologic agents of (muco) cutaneous mycoses. Etiologic agents of subcutaneous mycoses. Etiologic agents of deep mycoses. Etiologic agents of paramycoses. <br />
SYSTEMATIC PARASITOLOGY <br />
Parasitic Protozoa of medical interest. Life cycle of most important blood and tissue parasitic protozoa: haemoflagellates (Leishmania, Trypanosoma); human malaria parasites; Toxoplasma gondii; free-living amebae (Acanthamoeba, Naegleria). Life cycle of most important intestinal and urogenital parasitic protozoa: host-associated amebae (Entamoeba histolytica); ciliate (Balantidium coli); coccidia (Cryptosporidium, Cyclospora, Isospora); microsporidia; flagellates (Dientamoeba fragilis, Giardia intestinalis, Trichomonas vaginalis). Parasitic helminths of humans. Life cycle of most important blood and tissue parasitic helminths: cestodes (Echinococcus - hydatidosis; Taenia solium - cysticercosis); nematodes (Filaria, Trichinella, Toxocara); trematodes (Fasciola, Schistosoma). <br />
Life cycle of most important intestinal parasitic helminths: cestodes (Diphyllobotrium latum, Hymenolepis nana, Taenia saginata, Taenia solium); nematodes (Enterobius vermicularis, Ascaris lumbricoides, Ancylostoma, Strongyloides stercoralis, Trichuris trichiura). <br />
Notes on most medical interest important parasitic arthropods of medical interest. <br />
Notes on most important antiparasite drugs. <br />
SYSTEMATIC VIROLOGY <br />
Morphological and structural characteristics. Introduction to cultural characteristics and identification, pathogenesis of infections, epidemiology, prophylaxisand therapy relative to : <br />
Picornavirus, Ortomixovirus, Paramixovirus, Rabdovirus, Reovirus, Togavirus, Filovirus, Retrovirus, Adenovirus, Herpesvirus, Poxvirus, Hepatitis viruses, Papovavirus. <br />
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Full programme

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Bibliography

- M. Bendinelli, C. Chezzi, G. Dettori, N. Manca, G. Morace, L. Polonelli, M.A. Tufano - <br />
"MICROBIOLOGIA MEDICA: BATTERIOLOGIA, MICOLOGIA, VIROLOGIA. Gli agenti infettivi dell'uomo: biologia, azione patogena, laboratorio. " Monduzzi Editore <br />
- I. De Carneri - Parassitologia Generale ed Umana, Casa Editrice Ambrosiana, Milano. <br />
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Teaching methods

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Assessment methods and criteria

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Other information

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