OCCUPATIONAL MEDICINE

Mechanism of action and effects of the following toxic substances: solvents (aliphatic, aromatic, chlorinated), metals (arsenic, cadmium, chromium, mercury, manganese, lead), pesticides (organophosphates, organochlorines, pyrethroids). Acute and chronic poisoning by heavy metals (Cd, Cr, Pb, Hg, Mn). Mechanisms of chemical carcinogenesis and identification of the main occupational cancer. Mechanisms of neurotoxicity and main toxic neuropathies (central and peripheral). Illness and work-related illness at work, and the role concasuale ACTIVITY working in the genesis of common diseases such as pulmonary, osteoarthropathies, heart disease. Organ diseases: (i) broncopmeumopatie: allergic asthma, extrinsic allergic alveolitis, chronic obstructive bronchitis, pneumoconiosis, (ii) nephropathy, (iii) liver (direct and immunotoxic), (iv) blood dyscrasias (v) osteoarthropathies. Industrial noise and hearing loss; characteristics of hearing loss from noise. Control of the state of health of workers: health surveillance. The periodic preventive health assessments. The occupational history.