PHARMACEUTICAL TECHNOLOGY (WITH PRACTICAL EXERCISE)
Learning outcomes of the course unit
to acquire a deep-rooted theoretical and practical knowledge of the fundamental principles of pharmaceutical formulation
to develop the ability to apply these principles to specific problems in the formulation science;
toacquire a comprehensive understanding of how pharmaceutical dosage forms are developed, manufactured and controlled.
toacquire the independent learning ability required for continuing professional development
It is preferable to have already passed the exams of “general chemistry” and “organic chemistry”.
Course contents summary
Medicines and pharmaceutical dosage forms
Italian and European Pharmacopoeias
Disperse systems rheology
Good laboratory Practices
Pharmaceutical Processes: Particle size reduction, Mixing, Drying, Filtration, Sterilization, Dissolution, Granulation
Basic principles of biopharmaceuticspharmacokinetics
Pharmaceutical ingredients:active principles, excipients, packaging materials
Galenic development: pharmaceutical preformulation and formulation, packaging
Stability of pharmaceutical products
Conventional pharmaceutical dosage- forms: Solid dosage forms (Powders, Granules, Capsules, Tablets,pellets, suppositories), liquid dosage forms (solutions, suspensions,emulsions), semisolid dosage forms (ointments, gels, pastes, creams), sterile products
Administration routes and pharmaceutical dosage forms: oral, dermatological, parenteral, ocular,auricular, nasal, inhalation, rectal, vaginal.
Sera and vaccines
P. Colombo, PL Catellani, A. Gazzaniga, E. Menegatti, E. Vidale, Principi di Tecnologie Farmaceutiche, CasaEditrice Ambrosiana, Milano (2004)
M. Amorosa, Principi di Tecnica Farmaceutica, Libreria Universitaria L. Tinarelli, Bologna (1998).
Farmacopea Ufficiale della Repubblica Italiana, XI Edizione, Istituto Poligrafico e Zecca dello Stato, Roma (2002)
The course includes theoretical classes and practical works.