MEDICAL GENETICS
ACCADEMIC YEAR2009/2010
COD. 14422
dati insegnamento:
DEGREE: MEDICINA E CHIRURGIA
TYPE OF COURSE: COMPULSORY SUBJECTS, CHARACTERISTIC OF THE CLASS
LECTURERS:
SAVI Mario
ACADEMIC YEAR: 2009/2010
YEAR OF STUDY: 3
SEMESTER: Second semester
NUMBER OF CREDITS: 0
UNIT COORDINATOR: SAVI Mario
CONTACT HOURS:
Learning outcomes of the course unit
The purpose of this course is to provide an in-depth background in histocompatibilty (MHC-HLA) applied to clinical transplantation.
Prerequisites
Student must have basic knowledge in biology, immunology and genetics.
Course contents summary
Structure and biological role of MHC-HLA molecules. Genetics of HLA antigens in populations and families. Tissue typing methods (serology and molecular). HLA in clinical settings: tissue and organ transplantation. HLA compatibility and graft survival.
Recommended readings
Browning M, McMichael A: HLA and MHC: Genes, Molecules and Function. BIOS Ed
