VETERINARY MEDICAL CLINIC
Learning outcomes of the course unit
students are expected to learn the general principles of food and xenobiotic toxicology as well as the toxicology of certain substances classed as doping. The main principles of toxicokinetics and toxicodynamics in order to find out modes of assumption, digestion, absorption , distribution, metabolism and elimination of the main toxins. Chemical characteristics, sources of contamination, mechanism of action and elimination routes of the main toxins. Chemical characteristics, mechanism of action, efficacy, toxic components and elimination phases of doping drugs (beta-agonists and anabolic steroids). Techniques for obtaining and producing technological proteins, with particular emphasis on yeast lysates and their use in muscular protein anabolism.
general chemistry; organic chemistry
Course contents summary
xenobiotics: definition, chemical characteristics, toxicity;
principles of toxicokinetics and toxicodynamics;
main xenobiotics contained in food: mycotoxins (aflatoxins, ochratoxin), pesticides (organochlorates, organophosphorics, carbamates), nitrites and nitrates, heavy metals (cadmium, mercury, fluorine);
drugs and doping: toxic aspects of beta-agonists and anabolic steroids;
nutrition and muscular hypertrophy: technological proteins, yeast lysates;
Casarett & Doull's. Tossicologia. ed. AMSI
classroom lectures with the use of audiovisual aids (transparencies, video projector and power point programs, photocopies and scientific articles). Written test on all the chapters covered during the course with final oral assessment.