MEDICAL GENETICS
Course unit partition: BORGO VAL DI TARO/FIDENZA

Academic year 2008/09
1° year of course -
Professor
Academic discipline
Genetica medica (MED/03)
Field
Ambito aggregato per crediti di sede
Type of training activity
Affine/Integrativa
10 hours
of face-to-face activities
1 credits
hub: BORGO VAL DI TARO/FIDENZA
course unit
in - - -

Course unit partition: MEDICAL GENETICS

Learning objectives

<br />The course is thought as an introduction to genetics starting from the mendelian theory of inheritance to molecular genetics. The purpose of the course is to gain understanding of the principles of heredity, the relationships between the genes and normal or disease traits and the current advances in genetics applied to humans.

Prerequisites

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Course unit content

<br />Mitosis, meiosis. Principles of mendelian inheritance (Mendel’s laws), physical basis of mendelian inheritance, expression and interaction of genes, crossing over and linkage, mapping, biochemical nature of genetic material, replication and repair of DNA, the genetic code, the “central dogma” of molecular genetics, mutation. Mitochondrial heredity. Polymorphisms, multiple alleles (ABO and MHC systems). Mechanisms of genetic transmission in humans. Gene structure and function. Mechanisms of gene regulation in prokaryotes (the operon model) and eukaryotes. Human cytogenetics and chromosomal abnormalities. Polygenic inheritance. Principles of population genetics. Principles of genetic manipulation and recent developments in molecular genetics diagnosis of diseases.

Full programme

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Bibliography

<br />
Campbell NA, Reece JB, Biologia, Genetica Zanichelli Ed<br />
Novelli G - Giardina E : Genetica medica pratica, Aracne editrice, Roma

Teaching methods

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Assessment methods and criteria

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Other information

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