Learning outcomes of the course unit
This course aims to provide the informations and the scientific backround to approach correctly the main topics of Clinical Biochemistry so as to figure out the complexity concerning the biological samples, the possible sources of error and the valuable amount of information therein. This knowledge is needed especially by a professionals working in clinics or surgery departments.
There are no obligatory prerequisites, but Clinical Biochemistry is an interdisciplinary science and needs the basic knowledge in Biology, Anatomy, Physiology, Chemistry and Biochemistry
Course contents summary
- Kind of laboratory test: purposes and usefulness.
- Biological specimens: instruction for optimal collection, treatment and conservation (avoiding pre-analytical variation).
- Analysis of biological samples; analytical techniques and instrumentations
- Analytical and post-analytical variability affecting the laboratory data. Clinical laboratory quality assurance
- Kits for diagnostic tests. Current waived test. Implementation and monitoring of POCT.
- Markers of function or damage of some organs and systems. Index of cytolysis, clinical enzymology. Main cardiac, hepatic, renal and tumor markers. Toxicology, therapeutic drug monitoring; sport doping and substances of abuse control
- Urine analysis
- Laboratory tests in pregnancy. Maternal and fetal reference values
- G. Kellerman. Valori anormali di laboratorio. McGraw-Hill.
- L. Spandrio. Biochimica Clinica. Ed. Sorbona – Milano.
- R.A. Sacher, R.A. McPherson Interpretazione clinica degli esami di laboratorio. McGraw-Hill, New York.
The final oral examination is about the topics of the course; the student needs to demonstrate to have understood and to be able to manage the essential meanings of every section of the program.