STRUCTURE AND FUNCTION OF BIOMOLECULES
| STRUCTURE (0 credits) | STRUCTURE (1 credits) |
| FUNCTIONAL NETWORKS IN COMPLEX ORGANISMS unit B (1 credits) | FUNCTIONAL NETWORKS IN COMPLEX ORGANISMS unit A (1 credits) |
| BIOMOLECULAR STRUCTURE AND DYNAMICS (1 credits) |
Learning outcomes of the course unit
To provide the bases for the comprehension and the study of the molecular mechanisms of membrane transport.
Acquisition of the knowledge on:
- Cytological and molecular characteristics of the mitotic and meiotic cell cycle;
- Cytological and molecular mechanisms that regulate cell differentiation during preimplantation development
- Totitpotent, pluripotent, multipotent and unipotent stem cells; stem cell plasticity;
- Cell reprogramming.
Knowledge of the molecular models underlying the functions of the chemosensory systems
The course is aimed to give students basic understanding of physiological mechanisms involved in homeostatic balance. Specific examples will be proposed to highlight the pivotal role of the hypothalamus in integrative processes.
Give students a basic knowledge of the principles and practise of the most important methods to determine the structure, the conformational stability and dynamics of proteins in solution.
Prerequisites
Knowledge of basic biochemistry and cell biology is required
Course contents summary
Module Prof. Maurizio Zuccotti
Acquisition of the knowledge on:
- Cytological and molecular characteristics of the mitotic and meiotic cell cycle;
- Cytological and molecular mechanisms that regulate cell differentiation during preimplantation development
- Totitpotent, pluripotent, multipotent and unipotent stem cells; stem cell plasticity;
- Cell reprogramming.
Module Prof. Giancarlo Gazzola
Biomembrane composition, structure and turnover. Transport kinetics. Structure and function of transport proteins that form, propagate or dissipate solute gradients. Regulation of plasma membrane transport. Selected techniques in membrane transport.
Module Prof. Roberto Tirindelli
Knowledge of the molecular models at the base of the functions of the chemosensory systems
Module Prof. Giuseppina Basini
The course is aimed to give students basic understanding of physiological mechanisms involved in homeostatic balance. Specific examples will be proposed to highlight the pivotal role of the hypothalamus in integrative processes.
Module Prof. Lorella Franzoni
Considering the significant development and relevance of the structural proteomics, this course is designed to give students a basic knowledge of the principles and practise of the most important methods to determine the structure, the conformational stability and dynamics of proteins in solution.
Recommended readings
Sherwood, Klandorf, Yancey
Fisiologia degli animali - dai geni agli
Article given by the teachers
Proper reference to the texts of biochemistry and cell biology used in previous courses is recommended. Lectures will be supported by slides and scientific literature, which will be provided to the students.
