Learning outcomes of the course unit
Acquisition of essential knowledge about: bacteria, fungi, protozoa and viruses; host-pathogen interactions and pathogenesis of infectious diseases; mechanisms of action and use of common antimicrobial and antiviral agents; host immune response and prevention of infectious diseases.
Course contents summary
Origins and evolution of microorganisms and Microbiology. Microscopic observation of microorganisms and viruses. Structure and functions of the prokaryotic cell. Fungi. Protozoa. Viruses. Viroids and prions. Classification of microorganisms and viruses. Microbial growth and metabolism. Cultivation of microorganisms and viruses. Methods for microbial count. Elements of microbial genetics. Host-pathogen interactions. Normal flora of humans. Microbial pathogenicity and virulence factors. Viral pathogenesis. Common infectious diseases. Innate and acquired antimicrobial and antiviral immunity. Chemoprophylaxis and immunoprophylaxis of infectious diseases. Physical and chemical means against microorganisms and viruses. Antibacterial, antifungal, antiprotozoan and antiviral agents. Pharmaceutical Microbiology: Industrial and Pharmaceutical Microbiology; Evaluation of mutagenic potency of chemical compounds: the Ames test; Recombinant DNA and pharmaceutical products.
P. MAZZA, C. DA CARRO. "Microbiologia Farmaceutica", Società Editrice Farmaceutica, Milano.
Testi da consultare:
HUGO-RUSSELL. "Microbiologia Farmaceutica", Editrice EMSI, Roma.
M. LA PLACA. "Principi di Microbiologia Medica", Società Editrice Esculapio, Bologna.
M. BENDINELLI, C. CHEZZI, G. DETTORI, N. MANCA, G. MORACE, L. POLONELLI, M.A. TUFANO. "Microbiologia Medica gli agenti infettivi dell’uomo: biologia, azione patogena, laboratorio", Monduzzi Editore, Bologna.