GENETICS AND MUTAGENESIS

 Part 1 - DNA and mutations
-         DNA structure, Watson and Crick model
-         DNA replication
-         Causes of genetic instability of DNA
-         Spontaneous mutations
-         Mechanisms
-         Induced mutations and causes
-         Mutagens and mechanisms
-         Mutations and mutants
-         Relationships among genotype and phenotype

Part 2 - Mutagenesis tests
-         Mutagens and environmental mutagens
-         Mutagenesis tests: definitions, uses, principles
-         Mutagenesis tests with microbes, cells, animals, plants
-         Mutagenesis tests and genetic diseases in man
-         Mutagenesis tests and relationships with carcinogenesis and teratogenesis tests

Part 3 - Hypersensitivity to environmental pollutants
-         Modes of exposure
-         Exposure biomarkers
-         Effect biomarkers
-         Susceptibility biomarkers (hypersensitivity)
-         Ecogenetic markers
-         Correlations among biomarkers