ORGANIC CHEMISTRY (UNIT A)
Learning outcomes of the course unit
To introduce the student to the basic concepts of Organic Chemistry and to the properties and reactivity of the different classes of organic compounds.
To successfully follow the course and pass the examination it is fundamental to possess most of the knowledge and concepts treated in the course of 'Chimica Generale'. In particular, fundamental are the concepts related to the electronic structure of the atoms, to the chemical bond, to thermodynamics (with special regard to the chemical equilibria and to acid-base equilibria) and to the chemical kinetics.
It is not compulsory to have passed the examination of Chimica Generale, but it is strongly recommended to be in possess of most of the concepts related to such course before attending the lectures of Chimica Organica.
Course contents summary
he students will be first introduced to the basic theories of VSEPR and of the valence bond for the description of organic molecules. Some basic concepts of chemical thermodynamics and kinetics will be also reminded with particular attention to 1st and 2nd order reactions, to chemical catalysis and to competitive reactions. The concepts of nucleophile and electrophile will be compared with those of Brønsted-Lowry and Lewis acid and base. The concepts of organic stereochemistry will be described together with the stereochemical nomenclature and properties of the stereoisomers with particular attention to biological and pharmaceutical world.
A systematic survey of the structure, properties and reactivity of organic molecules, divided by functional groups, will be undertaken. In particular this analysis will include the following classes of organic compounds: Alkanes snd Cycloalkanes; Alkenes and Alkynes; Alkyl halides; Alcohols, Ethers and Thiols; Benzenes and Aromatic compounds; Amines; Ketones and Aldehydes; Carboxylic acids and their derivatives.
In parallel to this theoretical part, a series of exercises will be presented and solved during separate tutoring lectures aiming at applying the concepts learnt and to provide a constructivist approach to learning organic chemistry.
· W. Brown, T. Poon: Introduzione alla Chimica Organica, 3^ Edizione, EdiSES, Napoli.
To be consulted
· N. L. Allinger, M. P. Cava, D. C. De Jongh, C. R. Johnson, N. A. Lebel, C. L. Stevens, Chimica Organica, 2^ Edizione, Zanichelli, Bologna.
· W. H. Brown, C. S. Foote: Chimica Organica, 2^ Edizione, EdiSES, Napoli.
· J. McMurry, Chimica Organica, 1^ Edizione, Zanichelli, Bologna.
Theoretical explanations (4 hours/week during 13 weeks) together with tutoral activity (2 hours/week) consisting in exercises solved in classroom by the students and aimed at applying and reinforce the concepts learned.
The examination consists of a written and an oral proof.
At the half and at the end of the semester, it is possible to attend two intermediate written proofs regarding the first and second part of the programme, respectively. Who will pass both the intermediate proofs can directly access the oral examination.