The course is proposed to supply to the students general concepts on cellular and molecular immunology, innate and acquired. Initially, general knowledge about the structural and functional characteristics of the various components of the immune system will be given. The, it will be given detailed explanations about the manner of operation by which the immune system recognizes antigens and responds to them.
Course contents summary
General properties of the immune response: innate immunity (natural) immunity and specific (acquired)
Primary and secondary lymphoid organs
Barriers against infection.
Immune system cells: mononuclear phagocytes, T and B lymphocytes, NK cells, dendritic cells
Innate immunity. Phagocytosis.
Antigens and antibodies: molecular structure of antibodies, the binding
antigen-antibody, antibody functions
General features of the maturation of B lymphocytes and expression of genes
General features of the maturation of T lymphocytes
The major histocompatibility complex (MHC)
Activation of T lymphocytes
Activation of B lymphocytes
Humoral and cell-mediated immunity
Regulation of immune responses
One text chosen between the following :
T Doan. Le basi dell’immunologia. Zanichelli.
Abbas. Immunologia cellulare e molecolare
Frontal lesson with the use of supports audiovisual, argument in classroom with the students, supply of the audiovisual aids, talks with the student upon request.
The final appraisal involves one written verification according to the calendar of examination of the Course.