ECO-TOXICOLOGY

Part I: From toxicology to ecotoxicology
Analysis of toxic effects:
-    acute, chronic and sublethal effects
-    response: binary and continuous variables
-    experimental design and analysis of concentration-response data
-    limits of laboratory tests

Part II: Application in environmental toxicology
General criteria for selecting test types and methodology.
Toxicology of aquatic systems:
-    tests with freshwater and marine organisms
-    sediment toxicity tests.
Toxicology of terrestrial systems.
Biomarkers: principles and applications

Part III: Prediction of toxicity and environmental quality criteria
Quantitative structure-activity relationship (QSARs): principles and applications
Environmental quality criteria: the different approaches to their quantification
Complex mixtures
Toxicity identification and evaluation (TIE)

Part IV: Biodegradability and environmental fate
Physical-chemical properties of toxicants in predictive ecotoxicology.
Degradation processes
Bioaccumulation, bioconcentration and biomagnification.
Fate models

Part V: Risk  assessment
General principles and applications.
Legislation

Laboratory practical
Acute toxicity tests with freshwater invertebrates