Learning outcomes of the course unit
To acquire knowledge of the structure and reactivity of organic molecules, with particular attention to the biological substances. To acquire knowledge on classification and nomenclature of the organic compounds by the identification of their functional groups and, through these, on their reactivity. To learn the concepts of isomerism, conformation and stereochemistry of organic molecules and of their consequences in biological systems. To learn the principal concepts characterizing the reactivity of organic compounds in radicalic, electophilic and nucleophilic reactions. To know the functional groups and properties of some important classes of biological compounds, such as carbohydrates, triglycerides and amino acids.
To aquire experience on the principal laboratory techniques for the purification and modification of organic compounds.
General and Inorganic Chemistry
Course contents summary
Theoretical part (4 credits)
1-The covalent bond and the shape of molecules. 2-Alkanes and Cycloalkanes. 4-Stereochemistry. 5-Alkenes and Alkynes. 6-Aromatic compunds. 7-Haloalkanes. 8- Substitution and elimination reactions, mono- and bimolecular. 9-Alcohols, ethers. 10-Aldehydes and kentones . 11- Introdiction to the chemistry of carbohydrates. 12- Carboxylic acids and their derivatives. 13-Structure of triglycerides. 14-Amines and amino acids. 15- Structure of peptide and proteins.
Practical part.(2 Credits)
Tutorials: written exercises Laboratory activities:1) Liquid-liquid exctraction of a compound using acid-base aquilibria . Melting point determination. Qualitative anaysis using thin layer chromatography (TLC). 2)Puification of alcohols using distillation. Quantitative analysis of purity by gas-chromatography. 3) Structure and reactivity of carbohydrates. Mutarotation of glucose. Saccharose hydrolysis. Properties and hydrolysis of starch. 4) Synthesis of an ester. More information can be found at the web site: http://biotecnologie.unipr.it/
W.H. Brown T. Poon “Introduzione alla Chimica Organica” Terza Edizione. EdiSES 2005.• J. Mc Murry “ Fondamenti di Chimica Organica” Terza Edizione. Zanichelli, 2005. More detailed textbooks: Brown, Foote, Iveson “Chimica Organica” III Edizione EdiSES (2006).• K. Peter, C. Vollhardt, N.E. Schore “Chimica Organica” 3 Edizione. Zanichelli (2005). J. McMurry “Chimica Organica” 6 Edizione. Piccin (2005). P.Y. Bruice “Chimica Organica” EdiSES (2005) Tutorials .M.S.Erickson: “Guida alla soluzione dei problemi di Chimica Organica” Edi Ses. (2006) Laboratory Textbook:R.M. Roberts, J.C. Gilbert, S.F. Martin : ' Chimica Organica Sperimentale' Zanichelli Editore (1999).
Teaching methodology: frontal lectures (4 credits); tutorials and laboratory activities (2 credits)
Examination method: Intermediate tests during the course and final written and oral examination