Learning outcomes of the course unit
The student will achieve the fundamental knowledge on cell pathology and cell death. Causes and mechanisms of genetic diseases (single-gene disorders) will be treated to simplify the knowledge of gene therapy principles. The subject “Cancer” will be face from molecular, cellular and histological point of view to offer a panorama of the potential biotechnological applications.
Course contents summary
1. Cell injury and cell death
2. Cellular pathology: Cellular adaptation; Intracellular accumulations; Cellular aging 3. Genetic disorders: Transmission patterns of single-gene disorders; Biochemical and molecular basis of single-gene disorders; Some example of single-gene disorders
4. Neoplasia: Morphologic and biologic properties of tumor cells; The molecular basis of cancer; Tumor progression, invasion and metastasis; Benign and malignant neoplasms; Principles of tumor classification
Robbins: Pathologic basis of disease