Learning outcomes of the course unit
To bring mechanisms and nature of toxic effects of drugs and xenobiotics to student's knowledge.
It is necessary to pass the Pharmacology examination.
Course contents summary
-First principles of toxicity
-Experimental toxicology, evaluation of toxicological risks, mechanisms and tests of toxicity
-ADME of toxic substance
-Metabolism of xenobiotics
-Cancerogenesis, teratogenesis and mutagenesis
-Idiosincrasic and allergic reactions. Interactions between xenobiotics
-Metals, Solvents, Pesticides, IPA, PCOD, PCB
-Toxicology of biotecnological products
- Poisons and antidotes
-Central Nervous Sistem (CNS)
-ERNEST HODGSON: “Tossicologia Moderna”, EdiSES
-CASARETT & DOULL’S: "Tossicologia: fondamenti dell’azione delle sostanze tossiche", Ed. EMSI,
-W.A. HAYES: "Principles and Methods of Toxicology", III Edition, Raven Press.
-C.L. GALLI, E. CORSINI, M. MARINOVICH “Tossicologia”, Piccin
The oral examination will be about the entire program. Students must demonstrate a good comprehension of principal parts of each topic.