TOXICOLOGY
cod. 03033

Academic year 2009/10
4° year of course - First semester
Professor
Academic discipline
Farmacologia (BIO/14)
Field
Discipline biologiche e farmacologiche
Type of training activity
Characterising
72 hours
of face-to-face activities
9 credits
hub:
course unit
in - - -

Learning objectives

<br />
To provide fundamental knowledge and understanding of the nature and mechanisms of adverse and toxic effects of drugs and foreign substances.

Prerequisites

Pharmacology and pharmacotherapy

Course unit content

<br />
General section<br />
-         Fundamentals of toxicology<br />
-         Absorption, distribution and excretion of toxic compounds.<br />
-         Biotransformation of xenobiotics<br />
-         Genetic toxicology, carcinogenicity, reproductive and developmental toxicology.<br />
 <br />
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Special section<br />
 <br />
-         Toxicity testing and risk assessment<br />
-         Idiosyncrasy and allergic reactions, xenobiotic interactions.<br />
-         Toxicology of pesticides, metals, solvents and vapors, household products, natural toxins.<br />
-         Environmental toxicology: air, water and soil pollutants.<br />
-         Food toxicology: food additives and contaminants.<br />
-         Antidotal therapy<br />
-         Toxicology of biotech products<br />
-         Occupational toxicology

Full programme

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Bibliography

<br />
CASARETT & DOULL¿S: ¿Tossicologia: fondamenti dell¿azione delle sostanze tossiche¿, Ed. EMSI, Roma.<br />
GOODMAN & GILMAN¿S: ¿The pharmacological basis of therapeutics¿<br />
GREIM&DEML: Tossicologia, Ed. Zanichelli, Bologna.<br />
DOLARA: ¿Tossicologia generale ed ambientale¿, Ed. Piccin, Padova.<br />
GHI: Tossicologia, Ed. Minerva Medica, Torino.

Teaching methods

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Assessment methods and criteria

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Other information

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