Learning objectives
<br />To provide fundamental knowledge and understanding of the nature and mechanisms of adverse and toxic effects of drugs and foreign substances.
Prerequisites
Pharmacology and pharmacotherapy
Course unit content
<br />General section<br />- Fundamentals of toxicology<br />- Absorption, distribution and excretion of toxic compounds.<br />- Biotransformation of xenobiotics<br />- Genetic toxicology, carcinogenicity, reproductive and developmental toxicology.<br /> <br /> <br />Special section<br /> <br />- Toxicity testing and risk assessment<br />- Idiosyncrasy and allergic reactions, xenobiotic interactions.<br />- Toxicology of pesticides, metals, solvents and vapors, household products, natural toxins.<br />- Environmental toxicology: air, water and soil pollutants.<br />- Food toxicology: food additives and contaminants.<br />- Antidotal therapy<br />- Toxicology of biotech products<br />- Occupational toxicology
Full programme
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Bibliography
<br />CASARETT & DOULL’S: “Tossicologia: fondamenti dell’azione delle sostanze tossiche”, Ed. EMSI, Roma.<br />GOODMAN & GILMAN’S: “The pharmacological basis of therapeutics”DOLARA: “Tossicologia generale ed ambientale”, Ed. Piccin, Padova.
Teaching methods
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Assessment methods and criteria
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Other information
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