TOXICOLOGY
cod. 03033

Academic year 2008/09
4° year of course - First semester
Professor
Academic discipline
Farmacologia (BIO/14)
Field
Discipline biologiche e farmacologiche
Type of training activity
Characterising
72 hours
of face-to-face activities
9 credits
hub:
course unit
in - - -

Learning objectives

<br />To provide fundamental knowledge and understanding of the nature and mechanisms of adverse and toxic effects of drugs and foreign substances.

Prerequisites

Pharmacology and pharmacotherapy

Course unit content

<br />General section<br />-         Fundamentals of toxicology<br />-         Absorption, distribution and excretion of toxic compounds.<br />-         Biotransformation of xenobiotics<br />-         Genetic toxicology, carcinogenicity, reproductive and developmental toxicology.<br /> <br /> <br />Special section<br /> <br />-         Toxicity testing and risk assessment<br />-         Idiosyncrasy and allergic reactions, xenobiotic interactions.<br />-         Toxicology of pesticides, metals, solvents and vapors, household products, natural toxins.<br />-         Environmental toxicology: air, water and soil pollutants.<br />-         Food toxicology: food additives and contaminants.<br />-         Antidotal therapy<br />-         Toxicology of biotech products<br />-         Occupational toxicology

Full programme

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Bibliography

<br />CASARETT & DOULL’S: “Tossicologia: fondamenti dell’azione delle sostanze tossiche”, Ed. EMSI, Roma.<br />GOODMAN & GILMAN’S: “The pharmacological basis of therapeutics”DOLARA: “Tossicologia generale ed ambientale”, Ed. Piccin, Padova.

Teaching methods

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Assessment methods and criteria

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Other information

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