Learning objectives
Knowledge of the fundamental properties of the biological macromolecules, of the processes of degradation and biosynthesis of the main classes of biomolecules, and of the mechanisms of their regulation.
Prerequisites
It is required the exam of 'Chimica propedeutica biochimica - Metodologie e tecnologie biochimico-molecolari'
Course unit content
<br />Properties of biomolecules: nucleotides and nucleic acids, carbohydrates, lipids, aminoacids and proteins. Structure and function of proteins. Biological membranes. Enzyme catalysis and kinetics. Introduction to the metabolism: coenzymes, high energy bonds, redox potentials. Catabolism of glucose. Metabolism of glycogen. Gluconeogenesis. Tricarboxilic acids cicle and related rections. Electron transport, oxidative phosphorilation and respiratory control. Photosynthesis. Lipid metabolism: Fatty acids oxidation, keton bodies, fatty acids biosynthesi, cholesterol. Metabolim of aminoacids: transamination reactions, urea cycle. Nucleotides metabolism: ex-novo purines and pyrimidine biosinthesis. Ruminal fermentations.
Bibliography
Nelson. D.L. and Cox, M.M. "Lehninger principles of biochemistry"