GENERAL PATHOLOGY AND DIAGNOSTICH ANALYSIS
Learning outcomes of the course unit
The students will acquire knowledge on the main pathological processes of interest for their profession and will be able to apply it to situations of practical interest.
Adequate bases of anatomy, biochemistry and physiology.
Course contents summary
The course will provide some basic concepts of General Pathology, such as cell damage and Death, acute and chronic inflammation.
This information will be the basis to introduce the most common laboratory exams performed to evaluate the physiopathological consequences of exercise.
A) Elements of General Pathology
- Cell damage and death
- Acute and chronic inflammation
B) The blood
- Blood functions
- The complete blood count (CBC)
- The hematocrit and its alterations
- Leukocytes and leukocytosis
C) Indicators of tissue damage
- Organ-specific and non-organ-specific indicators
- Acute phase reaction, CRP and VES
- Fundamentals of immunopathology: Hypersensitivity and immunodeficiency
- Immunologic indicators of overtraining
- EIB and anaphylaxis
- Laboratory evaluation of immunocompetence
E) Organ damage
- Organ profiles
- The liver and the hepatic profile
- Liver toxicity of steroids
F) Diabetes Mellitus
- Physiopathological and biochemical bases
- The main types of DM
- The role of exercise in DM
- Esercise as the polypill
- Laboratory in the follow up of the diabetic patient
The reference text is Antoniozzi, Gulletta (eds.)
Medicina di laboratorio
Logica & Patologia Clinica
III ed., Piccin, Padova, 2019, which provides updated, pathophisiologically based information on clinical pathology and include a specific discussion on laboratory and exercise.
Other references will be provided during the lectures.
Lessons will be on site in compliance with safety standards, provided that further instructions on the ongoing health emergency are not implemented.
Lectures will be interactive and will be carried on through a dialogue between the teacher and the students. Examples of situations in which the laboratory helps to define exercise outcomes will be also provided so as to raise the interest of the students.
Supporting didactic material will be available on the specific, student-reserved platform (Elly) and will include slide presentations, audio-video aids or video-recording of the lessons.
Non-attending students are warmly invited to exploit the didactic material provided through the Elly platform.
Assessment methods and criteria
Oral examination. The examiner will choose one of the subjects included in the detailed program (and discussed during the lectures). The student will have to describe the subject and to discuss it with the examiner to demonstrate her/his competencies.