MICROBIOLOGY AND CLINICAL MICROBIOLOGY A
Learning outcomes of the course unit
Students have to know general characteristics of the pathogenic factors related to microorganisms and viruses. In addition, they must be able to apply this knowledge in the workplace.
Basic knowledge of biology, biochemistry and physiology are suitable to understand the course topics successfully.
Course contents summary
Main morphological and structural characteristics and life cycle of bacteria, fungi, viruses and parasites (protozoa).
Resident microbial population.
Pathogenicity of microorganisms and viruses. Antibacterial and antifungal drugs.
Main protozoa of medical interest.
Structural and functional characteristics of the prokaryotic cell. Comparison between prokaryotic and eukaryotic cells. Sporogenesis and germination. Metabolism and curve of growth. Host-bacterium interactions. Resident bacterial population. Mechanisms of pathogenicity. Antibacterial drugs. Mechanisms of resistance to antibacterial drugs.
General characteristics of fungi. Structure of the fungal cell and fungal colony. Yeasts and moulds. Reproduction of fungi. Mechanisms of fungal pathogenicity. Fungal dimorphism.
General features of viruses. Morphology and structure of viruses. Nucleic acids of viruses. Host-virus interactions: steps of viral infection. Effects of virus replication on host cell (productive and abortive infection; lysogeny; virus-induced transformation). Viral interference. Classification of viruses.
General features of protozoa. Life cycle of principal blood and tissue parasitic protozoa: Plasmodium sp., Leishmania, Toxoplasma gondii, free-living amoebae. Life cycle of the principal intestinal parasitic protozoa: intestinal amoebae (Entamoeba histolytica), Flagellates (Giardia intestinalis), Coccidia (Cryptosporidium spp.). Life cycle of the principal genito-urinary parasitic protozoa (Trichomonas vaginalis).
M. Bendinelli, C. Chezzi, G. Dettori, N. Manca, G. Morace, L. Polonelli, M.A.T u f a n o.
Microbiologia Medica. Batteriologia. Micologia. Virologia. Parassitologia. Monduzzi Editore
Lectures supported by visual aids will be used to present and discuss the contents of the course.
Assessment methods and criteria
The outcomes of learning will be verified through an oral examination.
By questions regarding the topics of the course it will be determined whether the student has achieved the goal of basic knowledge in the field, in order to access the following years of the bachelor course in TLB.