Learning outcomes of the course unit
Knowledge and understanding skills
1) To acquire the basic notions of pharmacognosy (source of active principles, technological processes, phytochemistry, classification of active principles)
2) To remember the botanical name of the plants
3) To acquire preliminary pharmacokinetic and pharmacodynamic notions for understanding the pharmacological activity of natural substances.
4) To know the pharmacological activity of the main natural molecules and their mechanisms of action
5) To Acquire ability in using the specific language of the discipline.
Knowledge and understanding applied skills
1) To apply the knowledge of the mechanisms of action of the natural molecules to define their pharmacological activity and use
1) To evaluate the validity of a phytotherapy product in independent manner
1) Possess the ability to synthesize information and effectively communicate it to specialists and non-specialists.
1) Develop skills and methodology that will allow you to study in a highly indipendent way.
2) Updating the knowledge through the consultation of scientific databases
There are not prerequisites. However, the following exams are highly recommended: Human anatomy/animal biology
Course contents summary
First part: introduction to pharmacognosy and preparation od drugs; hints of phytochemistry.
clkassification of active principles in the medicinal drugs.
Third part: therapeutical applications of drugs.
Medicinal plant and crude drug.
Phytocomplex and active compounds. Toxicity.
Basics of general pharmacology: pharmacokinetic and pharmacodynamic
Traditional medicine phytotherapy and nutraceuticals
Technology of natural medical products:
- harvesting, drying, grinding, squeezing, enfleurage, distillation, extraction.
Drug acquisition and preservation.
Phytochemisty and secondary metabolic pathways
VEGETAL ACTIVE PRINCIPLES:
- carbohydrates: mono/polysacchrides, starch, cellulose, gums, mucilages, pectins, destrans, inulin
- glycosides (cardioactive, cyanogenics, sulphurated, antraquinones, saponins).
- alkaloids: purinergics, tropanics, benzylisoquinolics, indolics, quinolinics.
- lipids: oils, fats, waxes. Omega-3 (atherosclerosis) and omega-6 fatty acids
- essential oils
Drugs acting on gastrointestinal system
- Aloe spp, Matricaria recutita, Althaea officinalis, Glycyrrhiza glabra, Foeniculum
vulgare, Pimpinella anisum, Illicium verum, Pimpinella Anisum, Ilicium Anisatum, Zingiber officinalis
- Constipation: manna, Rhamnus frangula, Rhamnus purshiana, Cassia spp, Aloe
spp, Rheum spp., aloe spp.
Drugs acting on CNS
- Stimolants: Coffea arabica, Thea sinensis, Theobroma cacao, Cola spp, Ilex
paraguayensis, Paullinia cupana
-Sedative: Valeriana officinalis, Piper methysticum, Passiflora incarnata, Melissa officinalis, humulus lupulus
-antidepressant; Hypericum perforatum
Drugs acting on cardiovascular system
- Antihyperlipidemic plants: Cynara scolimus, Allium sativum, Vaccinium myrtillus,
- Peripheral vascular disorders : Aesculus hippocastanum, Hamamelis virginiana, Vaccinium myrtillus, Ruscus aculeatus
Drugs acting on respiratory system
- saponins: Hedera helix, Poligala senega.
- essences: Eucaliptus globulus, Melaleuca spp, Menta piperita, Pimpinella anisum, Foeniculum vulgare, Myroxylon pereire, Myroxylon balsamum.
- mucilages: Althaea officinalis.
Drugs active on immune system:
- aloe spp., Eleuterococcus senticosus Maxim, Uncaria tomentosa, Astragalus membranaceus Fisch, Echinacea spp.
M.Tognolini, M.Chiavarini - Principi di Farmacognosia e Fitoterapia - UNINOVA
G. Fassina, E. Ragazzi-Lezione di Farmacognosia Droghe vegetali- CEDAM
F. Firenzuoli- Fitoterapia, guida all'uso delle piante medicinali- MASSON
P.M. Dewick- Chimica, biosintesi e bioattività delle sostanze naturali- Ed PICCIN
The lessons will be mainly frontal, but will be complemented by online bibliographic research in order to provide students with the ability to know reliable databases from which to obtain information onphytotherapy products.
The slides used to support lessons, as an integral part of the teaching material, will be uploaded weekly on the Elly platform.
Assessment methods and criteria
Oral examination, to be performed together with Plant Biology (as single exam).
Oral testing to be supported at the same time as the Plant Biology module (they are a single exam, both modules must be sufficient to overcome it).
Scale of assessment: 0-30
Weights and evaluation criteria:
1) Acquired knowledge (up to 14/30);
2) Ability to apply the acquired knowledge and to make connections between the covered topics (up to 10/30);
3) capacity to communicate concepts through the use of the specific language of the discipline (up to 6/30).