LEARNING OUTCOMES OF THE COURSE UNIT
The objectives of the Immulogy and Immunopathology course are to enable the acquisition of knowledge and understanding about mechanisms and alterations of the innate and adaptive immune response. Great emphasis will be given to the application of immunology in the context of laboratory practice in order to allow the student to apply the knowledge gained to understanding the mechanisms of action of antibodies and to identify potential antigens for the acquisition of useful skills for the future profession.
COURSE CONTENTS SUMMARY
Topics of Immunology and Immunopathology.Innate and acquired Immunology.
Autoimmune diseases, ,
immunodeficiencies and hypersensitivity.
Abbas A.K. Le basi dell'immunologia Edra V edizione
Del Gobbo V. Immunologia per le professioni sanitarie
PICCIN IV edizione
ASSESSMENT METHODS AND CRITERIA
Learning outcomes will be verified through an oral examination. Questions on the topics relating to the course will be used to test knowledge and understanding of the student in the discipline, and her/his ability to apply such knowledge and understanding in occupational contexts. Using the knowledge also acquired in other courses the student must demonstrate knowledge and understanding about the mechanisms of immune system activity in fisiologic and patologic conditions.
The topics in the program will be presented and discussed through lectures, with the aid of iconographic material, trying to involve the student so that it can be an active part of the lesson.
Innate immunity. Acquired immunity. Antigens. The structural and functional aspects of Antibodies. T and B lymphocytes and their receptors. The Major Histocompatibility System (MHC). Activation of B and T lymphocytes. Anatomy of the immune system. Effectors of the immune response: antibodies, T helper lymphocytes and cytokines, T cytotoxic lymphocytes. Immunity to bacteria, virus and protozoa. Vaccinations. Primary and secondary immunodeficiencies. Hypersensitivity. Immunological tolerance and autoimmune diseases. Tumor immunology. Transplantation.