Learning outcomes of the course unit
This course aims to provide the general informations and the scientific background to approach correctly the pratical aspects of Clinical Biochemistry applied to sport (also out of conventional labortories) so as to figure out the complexity of biological samples and the possible source of errors, with respect to the prevention of illicit expedients, athlete health or the role of the laboratory in the monitoring of training
There are no obligatory prerequisites, but Clinical Biochemistry is an interdisciplinary science and needs the basic knowledge in Biology, Anatomy, Physiology, Chemistry and Biochemistry
Course contents summary
Part of the course is devoted to the characteristics of biological samples, their collection and storage (Pre-analytical variability). The second part of the course regards the more common markers of organ function and damage, and the strategies of laboratory investigation concerning the use of methods and substances prohibited
Part 1. General Clinical Chemistry. Biological specimens consideration: instruction for optimal collection, treatment and conservation (avoiding pre-analytical variation).
Part 2. Analysis of biological samples; Analytical and post-analytical variability affecting the laboratory data. Kits for diagnostic tests.
Part 3. Current waived test. Point of care testing (POCT): use and application. Quality control in POCT. Specimen and its treatment in POCT. Auto-monitoring of some biochemical parameters.
Part 4. Outline of Clinical Biochemistry Markers of function or damage of some organs and systems. Index of cytolysis, clinical enzymology. Main cardiac, hepatic and renal . Toxicology, therapeutic drug monitoring; sport doping and abuse substances control
- Kellerman G. Valori anormali di laboratorio. Mc Graw Hill
- S.D.Ferrara. Doping Antidoping -Piccin
Assessment methods and criteria
The final oral examination is about the topics of the course; the student needs to demonstrate to have understood and to be able to manage the essential meanings of every section of the program.
The iconographic supports shown during the lessons will be available to the students since the beginning of the course