CLINICAL PATHOLOGY
cod. 06175

Academic year 2020/21
5° year of course - First semester
Professor
- Ovidio BUSSOLATI
Academic discipline
Patologia clinica (MED/05)
Field
Medicina di laboratorio e diagnostica integrata
Type of training activity
Characterising
14 hours
of face-to-face activities
2 credits
hub: -
course unit
in ITALIAN

Integrated course unit module: LABORATORY MEDICINE

Learning objectives

The student should (1) know the most commonly prescribed laboratory analyses in clinical pathology, (2) understand their role in diagnostic procedures, follow up and therapy monitoring, (3) properly evaluate their cost/benefit ratio and (4) apply this information to relevant clinical examples.

Prerequisites

Mandatory propedeutic examinations are defined by the Course Cuncil.
Relevant bases of Biochemistry, Physiology, Immunology and General Pathology should be adequately recalled.

Course unit content

- The laboratory in hematology.
- Laboratory evaluation of hemostasis.
- Clinical pathology of neoplasia
- Systemic parameters of inflammation and immunity

Full programme

A) Clinical pathology in hematology:
- Complete blood count (CBC)
- Anemia (sideropenic, of chronic disease, aplastic; sideroblastic, B12 and folate deficiency; hemolytic)
- Hemoglobinopathies
- Disorders of white blood cells
- Disorders of iron metabolism
- Lymphoproliferative and myeloproliferative disorders

B) The laboratory in hemostasis:
- Bleeding disorders: alterations of primary and secondary hemostasis
- Thromboembolic disease and thrombophilia
- DIC
- Monitoring of anticoagulant therapies

C) Inflammation and immunity:
- ESR and acuta phase proteins
- Complement, cytokines and chemokines
- Antibodies
- Cellular immunity
- Autoimmune diseases
- Immunodeficiency
- IgE-mediated hypersensitivity

D) Neoplasia:
- Tumor markers: concepts and classification
- Selected examples of tumor markers tumorali
- Genetic markers

Bibliography

Antoniozzi, Gulletta (eds.)
Medicina di laboratorio
Logica & Patologia Clinica
III ed., Piccin, Padova, 2019
The slides used during the lectures will be made available on the Elly Platform.

Teaching methods

The course will be held through lectures to Students either in the classroom (“in presenza”) or in synchronous-streaming (“in telepresenza”) on the Teams platform. Therefore, the opportunity of Student/Teacher interaction will be preserved both face to face and remotely, by the simultaneous use of the Teams platform.
Lectures will be supported by slide presentations, which will be available to students on the Elly platform (https://elly2020.medicina.unipr.it/).

Assessment methods and criteria

No interim examination. During the oral examination of the Course of Laboratory Medicine, one of the questions will concern Clinical Pathology.
The student should consult the site of the Course of Laboratory Medicine for further information.

Other information

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