BIOCHEMISTRY (C)
cod. 1002296

Academic year 2016/17
1° year of course - Second semester
Professor
- Federica Maria Angela RIZZI
Academic discipline
Biochimica (BIO/10)
Field
Attività formative affini o integrative
Type of training activity
Related/supplementary
14 hours
of face-to-face activities
2 credits
hub: PARMA
course unit
in - - -

Integrated course unit module: BIOCHEMISTRY AND MOLECULAR BIOLOGY

Learning objectives

To be able to describe and discuss the characteristics, the structure, the function and the mechanism of action of vitamins. To understand and apply the knowledge about the biochemical mechanisms of blood coagulation, calcium homeostasis maintenance.

Prerequisites

Before taking the exam of "Biochimica e Biologia Molecolare" student have to pass:
1) Chimica e Propedeutica Biochimica
2) Istologia ed Embriologia

Course unit content

Structure functions and mechanism of action of vitamins. Biochemical mechanisms of blood coagulation. Biochemical mechanisms of calcium homeostasis.

Full programme

Liposoluble Vitamins: nutritional aspects, structure, mechanism of action. Vitamin A and the mechanism light perception. Coordinated actions of vitamin D and parathyroid hormone in the regulation of serum calcium. Vitamin K: role in the maturation of clotting factors. Blood coagulation: molecular events of the intrinsic, extrinsic and common pathway. Mechanisms of clot dissolution.

Bibliography

Nelson DL, Cox MM: I principi di Biochimica di Lehninger, Zanichelli, Bologna.
Lewin, Krebs, Goldstein, Kilpatrick: Il gene. Zanichelli, Bologna.
Amaldi, Benedetti, Pesole, Plevani: Biologia Molecolare. Casa Editrice Ambrosiana, Milano.
Lieberman, Marks: Biochimica Medica, un approccio clinico. Casa Editrice Ambrosiana, Milano.
Baynes JW, Dominiczak MH: Biochimica per le discipline biomediche, Elsevier Mosby, Philadelphia.
Caldarera CM: Biochimica Sistematica Umana, CLUEB, Bologna.
Devlin TM: Biochimica con aspetti clinici. Wiley-Liss, New York.
Garrett RH, Grisham CM: Biochimica. Piccin, Padova.
Mathews CK, van Holde KE, Ahern KG: Biochimica, Casa Editrice Ambrosiana, Milano.
Murray RK, Granner DK, Mayes PA, Rodwell VW; Harper Biochimica, McGraw-Hill Libri Italia srl, Milano.
Siliprandi, Tettamanti: Biochimica Medica, Piccin. Padova.
Voet D, Voet JG: Biochimica John Wiley & Sons, USA.

Teaching methods

lectures

Assessment methods and criteria

Oral exam

Other information

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