Knowledge and understanding.
Students need learn the fundaments of the structure and component of the stem cell niches in endocrine and neuroendocrine organs of the adult;
Applying knowledge and understanding
Students must use molecular and cellular techniques for development of a protocol for the isolation, characterization, expansion and differentiation of endocrine and neuroendocrine stem cells.
Ability to reason about molecular and cellular protocol for cell niche and stem cell study appeared on an article of an international journal and/or PhD-thesis
Ability to understand and be understood in technical situations
Ability to summarize a technical procedure and to write a scientific progress report
knowledge of human histology and anatomy
Course contents summary
First lessons: fundaments and structure of the human endocrine and neuroendocrine organs
The following lessons: techniques for development of a protocol for the isolation, characterization, expansion and differentiation of endocrine and neuroendocrine stem cells
Functional anatomy of the stem cell niche.
Regenerative medicine in endocrinology: biomaterials and endocrine and neuroendocrine tissue regeneration.
Bioengineering ex situ endocrine organs and neuroendocrine
Biomaterials and regenerative medicine, biomechanics structural
International reviews and scientific commentaries will dispensed by the teacher
Oral lesson, lectures. Assimilation of scientific literature concerning the methods, the experimental protocols, the animal models, stem cell culture isolation and characterization procedures.
Assessment methods and criteria
End-of-term evaluation and continuous assessment. Written examination by a multiple (four) choice tests.
4 questions on the stem cell, the niche anatomy, the tissue regeneration. Students must answer correctly at least to 3 questions.