CHEMISTRY OF HETEROCYCLIC COMPOUNDS
Learning outcomes of the course unit
The course aims to give the students the knowledge of the heterocyclic chemistry of monocyclic and benzofused compounds, their nomenclature, properties and synthesis. Moreover the course intends to provide the students with the ability to understand the reactivity of the heterocyclic compounds. At the end of the course the student will have the expertise to analyze the chemical behavior of the main heterocyclic systems.
It is necessary to have knowledge of organic chemistry. To access the final examination the student must have passed the Organic Chemistry I exam.
Course contents summary
After the classification and nomenclature of heterocyclic compounds, the course will mainly describe aromatic heterocycles, in particular five- and six-membered monocyclic and benzo-fused systems, dealing with their reactivity, tautomerism, basicity (in the case of N-heterocyclic compounds) and synthesis.
Textbooks and reference books:
1. G. A. PAGANI, A. ABBOTTO, Chimica Eterociclica, Ed. Piccin.
2. D. SICA, F. ZOLLO, Chimica dei composti eterociclici farmacologicamente attivi, Ed. Piccin. 2008.
3. J.A. JOULE, K. MILLS, Heterocylic Chemistry, 5th Edition, Wiley-Blackwell Edition.
4. T. GILCHRIST, Heterocyclic Chemistry, Ed. Longman, 1997.
5. D. T. DAVIES, Aromatic Heterocyclic Chemistry, OUP Ed., Oxford Chemistry Primers, 1992.
Additional teaching material for students:
Pdf files of the lesson slides.
The course is carried out through frontal oral theory lessons, in order to give the students the knowledge about the nomenclature, preparation and reactivity of the main heterocyclic compounds. Exercises will be carried out with the maximum involvement of the students with the aim to favor the acquisition of skills and competences at the analysis retrosynthesis and reactivity of heterocyclic compounds.
Assessment methods and criteria
Verification of the achievements of the course will be carried out by a written examination. The written examination aims at verifying whether the student has acquired the knowledge and developed the skill in applying this knowledge and understanding in the analysis and resolution of the exercises.