Provide general principles of medicinal chemistry, evidencing the relationships between drug structure and their therapeutically relevant properties. Analyse the classification, the chemical, physicochemical and biological properties, the mechanism of action, structure-activity relationships and synthesis of drugs.
Course contents summary
In the first part, general themes will be addressed, including drug nomenclature, principles of pharmacokinetics, metabolism and mechanism of action, as well as basics on structure-activity relationships. The second part will be focused on the principal classes of antibacterials, antiviral and antitumor drugs.
Williams-Lemke: "Foye's Principi di Chimica Farmaceutica", PICCIN, Padova.
G.L. PATRICK: Introduzione alla chimica farmaceutica; Edises Napoli.
Oral lesson with slide projection.
Assessment methods and criteria
The student achievements will be evaluated by oral examination. Questions from the eaxminator and discussion will aim at establishing if the objectives of knowledge and comprehension have been achieved and if the studen is able to explain clearly and correctly the subjects.