Learning outcomes of the course unit
The course aims at providing to the students the fundamental knowledge of organic chemistry which allow them to understand the properties and the reactivity of organic compounds, starting point for the study of biochemistry
Course contents summary
The covalent bonds and the shape of the molecules.
Short overview on the following topics: electron structure of the atoms, bonds, intermolecular interactions.
Kinetic and thermodynamic aspects of the chemical reactions. Reaction energy graphics: transition state and intermediate.
Formula and structure of organic molecules, structural isomers, resonance.
Organic compounds classified on the basis of the functional groups.
Nomenclature, structure, physical properties and reactivity of: alkanes, cycloalkanes, alkenes, dienes, alkyl halides, alcohols, thiols, ethers, thioethers, amines, aromatic compounds, phenols, heterocyclic compounds, aldehydes, ketones, carboxylic acids and their derivatives compounds. Structures and main reactions of carbohydrates, lipids, amino acids, proteins.
Stereochemistry : conformational and configurational isomers, cis-trans isomerism, chirality, optical activity, absolute configuration. Importance of the chirality in biologic systems.
Reaction mechanisms. The main types of organic reactions. The main intermediates of organic reactions: carbocation, carbanions, carbon radicals
L. Binaglia, B. Giardina- Chimica e propedeutica biochimica, McGrawHill
W. H. Brown, Introduzione alla Chimica Organica, EdiSES, Napoli
Exercises on the reactivity of organic molecules will be discussed.
Examination will be based on written exrcises. Oral examination if request by the student or the teacher