GALENIC PREPARATIONS LABORATORY
Learning outcomes of the course unit
The objective of the course is
- to give to the students the information needed for verifying the formal and substantial correctness of the prescription according to the current laws and rules.
-to give to the student the practical notions about the preparations, controls and technological properties of most common immediate release dosage forms.
The expected learning outcomes are:
1) Knowledge and understanding: knowledge of excipients, fabrication methods, of controls, of technological properties of immediate release dosage forms.
2) Applying knowledge and understanding: ability to apply, in an independent way, the knowledge acquired for the preparation of a given dosage form.
3) Communication skills: ability to use the specific language for this specialistic discipline.
4) Making judgements: the capability to face the professional responsibilities of the galenic pharmacist
5) Learning skills: capability of using the knowledge and the basic elements acquired in the conduction of the work as galenic pharmacist. Capability of upgrade, through the scientific publications in the field of pharmaceutical technology.
It is necessary to have passed the exams of physiology and organic chemistry
Course contents summary
1) Legal issues concerning preparation, packaging and pricing of galenic preparation in pharmacy
2) Preparation and controls of conventional dosage forms:
- Oral powders
- Topical powders
- Liquid preparations for oral use
- Liquid preparation for topical use
- Topical semisolid dosage forms
- Vaginal preparations
- Rectal preparations
• Legal issues concerning the preparation, packaging and pricing of galenic preparation according
• Preparation and characterization of conventional dosage forms:
o Oral powders
o Topical powders
o Liquid preparations for oral use
o Liquid preparation for topical use
o Topical semisolid dosage forms
o Vaginal preparations
o Rectal preparations
Farmacopea Ufficiale della Repubblica Italiana, XII
Edizione, Istituto Poligrafico e Zecca dello Stato, Roma (2008);
-Medicamenta, Cooperativa Farmaceutica Milano, VII ED. 1992;
P. Colombo, P.L. Catellani, A. Gazzaniga, E. Menegatti, E. Vidale Principi di Tecnologie Farmaceutiche, Casa Editrice Ambrosiana, Milano (2004)
ENRICO RAGAZZI, «Galenica pratica, formulazione e tecnologia», Libreria Internazionale Cortina Padova
FRANCO BETTIOL, «Manuale delle preparazioni galeniche», Tecniche Nuove
The course will be carried out through frontal lessons (2CFU) during which the fundamentals, the theoretical and practical aspects of the compounding will be presented and discussed.
3 CFU will be devoted, then, to the practical preparation of different dosage forms with particular emphasis to the physico- chemical as well as legal aspects of the different operations.
Assessment methods and criteria
To acquire the final grade of the exam, the student must show to be have learned and to be able to use the basic concepts of each subject. In particular he/she should pass:
a) Practical exam consisting in the compounding of a preparation based on a prescription. The exams aims at verifying the practical skill acquired by the student as well as its capability to properly prepare a report on the prepared dosage form
b) Written exam, during the official dates established by the Dipartimento di Farmacia, aiming to verify the capability of the student to carry out calculation usually necessary during the pharmaceutical compounding).
The grade, expressed in thirtieths, will be based on the following criteria:
1. knowledge and comprehension (theoretical and practical) capability of the subjects studied;
2. personal judgements ability
3. appropriate use of the technical language;
4. ability to learn and deepen the topics studied.