DISEASES OF THE BLOOD
Learning outcomes of the course unit
a) knowledge of the anatomy and physiology of the hematopoietic system.
b) understanding a blood test.
c) knowledge of the etiology of the hematologic diseases (genetics, exposure to toxic agents, role of the environment).
d) ability to write down a report and to give an oral presentation.
Course contents summary
Teaching program:
a) structure of the bone marrow and the function of the hematopoietic system.
b) classification and clinical manifestations of the hematological disorders.
c) etiology and pathogenesis of the hematologic diseases: genetics, cytogenetics, biologic agents, the environment.
d) diagnostic issues.
e) hematopoietic stem cells: biology and clinical applications.
f) principles of therapy. Drugs. Side effects.
Course contents
1. the hematopoietic system
2. Bone marrow and peripheral blood sampling and film preparation
3. biology and clinical use of the hematopoietic stem cell
4. classification of the malignant and non-malignant hematological disorders
5. approach to diagnosis of the hematological disorders
6. sideropenic and megaloblastic anemia
7. severe aplastic anemia
8. acute leukemia
9. chronic leukemia
10. Hodgkin's lymphoma
11. non Hodgkin's lymphomas
12. multiple myeloma and monoclonal gammopathies
13. myelodysplastic syndrome
14. autologous and allogeneic hematopoietic stem cell transplantation
Recommended readings
Corso di malattie del sangue, di Tura e Baccarani; Esculapio Ed. 2011.
Malattie del sangue e degli organi ematopoietici, di Castoldi e Liso; McGraw Hill Ed. 2013; Core Curriculum Ematologia, McGraw Hill ed, seconda ed, 2014
Teaching methods
a) formal lessons;
b) panel discussion at the end of each lesson;
c) meetings.
Assessment methods and criteria
oral discussion
Other informations
All the slides presented during the formal lesson will be available.
