Università degli Studi di Parma

il mondo che ti aspetta

Target

Exchange students
Prospective students
Visiting scholars

About Us
General description of the institution

Our Mission and our Values

Academic authorities

Departments

The Italian university system

Facts and figures

Contact us
Studying
General admission requirements

Application procedure A.Y. 2019-2020

Academic calendar

General arrangements for the recognition of prior learning

Course catalogue - Academic Year 2019-2020

Course catalogue - Academic Year 2018-2019

Academic degree courses delivered in English language

Tuition fees and scholarships 2019-2020

Credits for sport activities

University Master Programmes

Postgraduate Schools

Research doctorates
Research
International research

Horizon 2020 - EU Programmes

ERC - European Research Council

EU funded projects

Temporary Fellowships for Research Activities
Services and Facilities
Arrangements for academic guidance

Learning services and facilities

Part-time employment for students

Language courses

Facilities for special needs students

Certification of disabilities

Sport facilities

Insurance

Financial support for students

Students associations
Living in Parma
Accommodation

The town

Cost of Living

Meals

Medical facilities

What's on in Parma

Leisure facilities

Emergency phone numbers

Home
Information on degree programmes

FORMULATION AND RELEASE OF BIOTECHNOLOGICAL DRUGS

ACCADEMIC YEAR2016/2017

COD. 1004742

dati insegnamento:

DEGREE: MEDICAL, VETERINARY AND PHARMACEUTICAL BIOTECHNOLOGIES

TYPE OF COURSE: SUPPLEMENTARY COMPULSORY SUBJECTS

LANGUAGE OF INSTRUCTION: Italian

LECTURERS:

NICOLI Sara

ACADEMIC YEAR: 2016/2017

YEAR OF STUDY: 2

SEMESTER: First semester

NUMBER OF CREDITS: 5

CONTACT HOURS: 35

INDIVIDUAL WORK HOURS: 90

Learning outcomes of the course unit

The purpose of this course is to provide a general knowledge of the role of the formulation on stability, release and bioavailability pf active compounds , with a particular attention to biotech drugs. A further aim of the course is to provide the students the tools for the elaboration of the information given so as to integrate them into their knowledge. In particular at the end of the course the student shall:
-have aquired a general knowledge on pharmaceutical formulations for biotech drugs
-be able to highlight, for every formulation/administration route, potentialities, limits and impact on patient therapy
-ba able to present (orally or in writing) the topics studied in a clear way and using a correct technical language

Prerequisites

Basic knowledge of anatomy, physiology and chemistry are required

Course contents summary

The first lecture of the course presents the impact that the formulation can have on the release of the active compound and on its bioavailability, with a particular attention to the biotech drugs. Then the conventional formulations (solutions, emulsions, suspantions, solid forms) will be illustrated as well as the innovativce approaches to increase drug bioavailability

Course contents

The program is the following:
General topics: BIOAVAILABILITY, BIOPHARMACY, POLYMERS, DIFFUSION
Conventional formulations: SOLUTIONS, EMULSIONS, SUSPENSION, COLLOIDAL DISPERSIONS. LIQUIDS FOR ORAL AND PARENTERAL ROUTES, SEMISOLID FORMULATIONS, POWDERS, TABLETS, CAPSULES
INNOVATIVE FORMULATIONS and CONTROLLED RELEASE: RESERVOIR and MATRICES, OSMOTIC SYSTEMS, GASTRORETENTIVE SYSTEMS, COLON DELIVERY, MUCOADHESION, MICROPARTICLES, NANOPARTICLES, LIPOSOMES, HYDROGELS, ORAL ADMINISTRATION OF BIOTECH DRUGS
Alternative administration route: TRANSDERMAL , BUCCAL, NASAL, PULMONAR DRUG DELIVERY, ORAL ADMINISTRATION OF PEPTIDE AND PROTEINS

Teaching methods

The course is organized with frontal lectures. The first lecture presents the rationale of the pharmaceutical formulations and highlight the background needed to deal with this course. Then, general topics such as bioavailability and bioequivalence, dissolution, diffusion, polymers, are presented. Finally, the different pharmaceutical formulations (conventional and innovative) and alternative delivery routes are explained in detail.

Assessment methods and criteria

The final examination is an oral examination and is organized so as to evaluate:
-the knowledges of the topic treated during the course
-the ability to understand and elaborate information
-the ability of applying general concepts to specific subjects
-the ability to relate the different topic studied with the knowledge aquired in the previous courses
-the pertinence of the written language (in terms of clarity and accuracy)

PARENT ACTIVITY

DRUGS AND MEDICINES

OTHER COURSES

YEAR: 1

BIOLOGICAL BASIS OF REGENERATION AND REPAIR
BIOLOGICAL BASIS OF REGENERATION AND REPAIR
BIOLOGICAL PHYSICAL CHEMISTRY
BIOMOLECULAR STRUCTURE AND DYNAMICS
BIOMOLECULAR STRUCTURE AND DYNAMICS
INTERACTION DRUG-BIOMOLECULES
PHARMACEUTICAL BIOCHEMISTRY
STRUCTURE AND FUNCTION OF BIOMOLECULES
STRUCTURE AND FUNCTION OF BIOMOLECULES
STRUCTURE, DIFFERENTIATION AND FUNCTIONS OF EUKARYOTIC CELLS AND NETWORK BETWEEN ORGANS
STRUCTURE, DIFFERENTIATION AND FUNCTIONS OF EUKARYOTIC CELLS AND NETWORK BETWEEN ORGANS

YEAR: 2

BIBLIOGRAPHY RESEARCH IN BIOMEDICINE
BIOETHICS
BIOTECHNOLOGIES APPLIED TO DIAGNOSTIC
BIOTECHNOLOGY IN CLINICAL PATHOLOGY
CYTODIAGNOSTICAL TECHNIQUES
DIAGNOSTIC OF ANIMAL TSE
DRUGS AND MEDICINES
ETHICAL AND LEGISLATIVE ASPECTS OF BIOTECHNOLOGICAL APPLICATIONS
EXPERIMENTAL MODELS
FINAL EXAM
FORMULATION AND RELEASE OF BIOTECHNOLOGICAL DRUGS
FUNCTIONAL ANATOMY OF STEM CELL NICHE
HISTOPATHOLOGICAL TECHNIQUES
LEGISLATION AND PATENTS
MOLECULAR BASES OF DRUG ACTION
MOLECULAR TECHNIQUES IN GENETIC DIAGNOSTICS
REGENERATION OF DIFFERENTIATED TISSUES
REGENERATION TECHNIQUES IN VISUAL DISEASES
REGENERATIVE MEDICINE IN ENDOCRINOLOGY
TECHNIQUES FOR ORAL TISSUE REGENERATION
TECHNIQUES FOR SKIN REGENERATION
TRAINING

Università degli studi di Parma

via Università, 12 - I 43121 Parma

P.IVA 00308780345

tel. +390521902111

email: protocollo@pec.unipr.it

> contact us
urp
twitter
facebook
linkedin
youtube
instagram

Legal Notes
Privacy
Access statistics