HEMATOPOIETIC STEM CELLS: BIOLOGY AND CLINICAL APPLICATIONS
Learning outcomes of the course unit
The objectives of the course will acquire the basic knowledge on hematopoietic stem cells and mesenchymal physiological and pathophysiological mechanisms that regulate hematopoiesis and on major diseases of the blood and blood-forming organs. Educational objective will also be to learn the main clinical applications of hematopoietic stem cells and in particular transplant procedures. Students will need to show ability to understand what is the physiology and pathophysiology of hematopoietic stem cells, hematopoiesis and blood diseases and must show competence on the notions that the student will acquire through the frequency of education and study.
The course will also aim to achieve autonomy judgment, communication skills and learning ability in the field of hematopoietic stem cell biology and their clinical applications
G. Castoldi e V Liso, Manual of Blood and bone marrow diseases
6th edition; Mc Graw Hill.
Hoffman et al.
Hematology, Basic principes and practice.
The modalities of teaching and teaching methods of the course will be lectures, participation in seminars and conferences and exercises in the laboratory of Hematology and bibliographical research. During the lectures will discuss the issues related to stem cells, hematopoiesis and blood diseases.
The course will be supported by laboratory exercises. The exercises will be individual and practices and their purpose is to provide the opportunity for each student to be able to measure in the design of autonomous solution to the real problems that will be made. These activities will be planned in such a way that within each exercise, the student can achieve practically the solutions of the problems outlined during theoretical lessons.
Assessment methods and criteria
The primary mode of verification will be to make interactive lessons with questions aimed at students and their active involvement in the discussion on the main issues discussed during class knowledge and the links between knowledge skills that are going to occur will focus on what are the characteristics of hematopoietic stem cells and mesenchymal cells, the notions haematopoiesis and pathophysiology, etiology and diagnosis of blood diseases and stem cell transplantation procedures and manipulation of hematopoietic stem cells in the laboratory.
A final check will be made through written test with open questions on the main topics discussed during the lectures.