LEARNING OUTCOMES OF THE COURSE UNIT
understand and interpret the clinical significance of laboratory tests
COURSE CONTENTS SUMMARY
L.Triolo: Medicine for health professionals. Ed Piccin. latest edition
ASSESSMENT METHODS AND CRITERIA
lectures and interactive teaching
Slides will be available at the end of the course.
Contents of the Course of Applied Pharmacology
• General information on drugs. Nomenclature, pharmaceutical forms, discovery and development of new drugs, drug prescription. Pharmacosurveillance.
• General principles of pharmacokinetics. Absorption, distribution, metabolism and elimination of drugs. Accumulation of drugs into the body.
• Routes of administration of drugs
• Bioavailability and Bioequivalence.
• Dosage of drugs and Therapeutic Regimens
• Principles of Pharmacodynamics: mechanism of drug action and molecular targets.
• Factors that modify the response to drugs
• Drug toxicity: intolerance and allergy. Idiosyncratic responses and principles of pharmacogenetics.
• Drug-drug interactions of clinical relevance.
• Drugs acting on the central nervous system. Benzodiazepines, antidepressants, adrenergic stimulants.
• Drugs for control of pain. Opioid analgesics. Local anesthetics. NSAIDs and acetaminophen.
• Competitive and depolarizing neuromuscular blockers. Botulinum toxin and direct antispasmodics.
• Steroidal anti-inflammatory drugs and immunosuppressants: focus on corticosteroids.
• Gastrointestinal drugs: antacids, histamine H2-receptor antagonists, proton pump inhibitors, antiemetics, prokinetics, anti-diarrhoics, laxatives.
• Cardiovascular drugs, antihypertensives, diuretics, antiarrhythmics, digitalis and other positive inotropes; coronaroactive drugs, drugs affecting hemostasis.
• Principles of chemotherapy and general information about major classes of antibacterial, antiviral and anticancer drugs