TOXICOLOGY
cod. 03033

Academic year 2016/17
4° year of course - First semester
Professor
Academic discipline
Farmacologia (BIO/14)
Field
Discipline biologiche e farmacologiche
Type of training activity
Characterising
72 hours
of face-to-face activities
9 credits
hub: PARMA
course unit
in ITALIAN

Learning objectives

Provide knowledge about the nature of toxic effects of xenobiotics. Provide the general principles of risk assessment

Prerequisites

pharmacology class

Course unit content

toxic action of xenobiotics and the main regulatory aspects; epidemiology

Full programme

General Section

· General principles of toxicology.

· Mechanisms of toxicity. Toxicity test.

· Absorption, distribution and excretion of toxic substances.

· Biotransformation of xenobiotics.

· Carcinogenesis, teratogenesis, mutagenesis.

 

special section

· Experimental toxicology, epidemiology and toxicological risk assessment.

· Idiosyncratic reactions and allergic diseases, interactions between xenobiotics.

· Toxicology of pesticides, metals, solvents, PAHs, PCB.

· Environmental Toxicology, gas

· food and nutrition Toxicology, Food Additives and Contaminants. Regulatory agencies.

· Occupational Toxicology

· Toxicology of biotechnology products.
 

Bibliography

teacher's slides

-ERNEST HODGSON: “Tossicologia Moderna”, EdiSES

-CASARETT & DOULL’S: "Tossicologia: fondamenti dell’azione delle sostanze tossiche", Ed. EMSI,

Roma.

-W.A. HAYES: "Principles and Methods of Toxicology", III Edition, Raven Press.

Tossicologia generale e applicata ai farmaci. Balduini-Costa. Ed EDRA

Teaching methods

classroom

Assessment methods and criteria

oral examination

Other information

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