GENERAL PATHOLOGY II
Learning outcomes of the course unit
The objectives of the General Pathology I course are to enable the acquisition of knowledge and understanding the mechanism of innate and specific immune system, the pathogenesis of the main immunopathologic diseases, the ABO blood and the rhesus (Rh) blood groups, and problems related to blood transfusion. The course allows the student to apply the knowledge gained in the context of biomedical laboratory.
Course contents summary
Blood and Hematopoiesis and components of Innate and acquired immune system. General features of acute and chronic inflammation and immunopathology. Immunoemathology and transfusional medicine.
Course contents
Blood and Hematopoiesis. Stem cells.
Innate immunity. Acquired immunity. The structural and functional aspects of Antibodies. T and B lymphocytes and their receptors. The Major Histocompatibility System (MHC). Activation of B and T lymphocytes. Vaccinations. Hypersensitivity. Immunologic tolerance and pathogenesis of autoimmune diseases. Transplantation. Immunodeficiency
General features of acute and chronic inflammation
ABO blood groups and serum antibodies. The rhesus (Rh) blood groups. Other blood groups. Haemolytic disease of the newborn.
Basic knowledge on the taking of a blood sample and fitness of donors.
Blood components and plasma by-products: properties, directions for use, preparation procedures and preservation.
Complications following blood transfusion and their handling.
Recommended readings
Parola M. “Patologia Generale” EDISES
Pontieri G.M. “Elementi di Patologia Generale” III edizione PICCIN
Teaching methods
The topics in the program will be presented and discussed through lectures trying to involve the student so that it can be an active part of the lesson.
Assessment methods and criteria
Learning outcomes will be verified through an oral examination. Questions on the topics relating to the course will be used to test knowledge and understanding of the student in the scientific discipline, and her/his ability to apply such knowledge and understanding in occupational contexts. Using the knowledge also acquired in other courses the student must demonstrate knowledge and understanding about the generality of immune system, immunopathology and immunoemathology.
