HUMAN PHYSIOLOGY, CLINICAL BIOCHEMISTRY AND CLINICAL MOLECULAR BIOLOGY
Learning outcomes of the course unit
-The knowledge of the mechanisms by which the human organism obtains and maintains the homeostasis at level of cell and tissue, the mechanisms of transport and communication and the basal metabolism.
-The knowledge of the functional mechanisms of the human body organs, the knowledge of their dynamic integration in apparatuses and the general mechanisms of functional control in normal conditions and in particular pathological conditions.
-The knowledge of the biological samples their variability, preservation and viability.
It is recommendable that the student is acquainted of the main concepts of Biology, Anatomy, Chemistry and Biochemistry.
Course contents summary
The course focuses on the mechanisms underlying the general functions of the cells as transports, electrical and chemical communication, mechanical activity, metabolism, the functions of the main apparatus of the body as cardiovascular, pulmonary, renal and endocrine.
The metabolism of the body will be studied with the aim of identifying the main molecular markers commonly employed in the clinical laboratory tests. There will be carried out the characterization of the different biological samples, their possible adulteration and the methods for their preservation.
Testi consigliati (uno a scelta):
-FISIOLOGIA, dalle molecole ai sistemi integrati.
E. Carbone, F. Cicirata, G. Aicardi.
W.J. Germann, C.L. Stanfield,
P.E. Di Prampero, A. Veicsteinas
- Biochimica per le discipline biomediche, J.W.Baynes, M.H.Dominiczak.. Casa Editrice Ambrosiana.
• Biochimica Clinica. L. Spandrio. Ed. Sorbona – Milano
Assessment methods and criteria
Oral exam with a final mark averaged with those of the two classes of the course .