This course provides a comprehensive summary of molecular properties and molecular mode of replication for the most important viral species that are agents of infections and morbidity for human species. Furthermore,provides a comprehensive summary of the host defenses:aspecific, natural or innate immunity, adaptative immunity, and a comprehensive summary of the interactions between the humoral as well as cellular molecules with relevant defensive actions.
Course contents summary
Viral multiplication and the different replicative modes showing RNA viruses s/s genome,RNA viruses d/s genome, linear or segmented, positive or negative sense of genome molecule. Several DNA and RNA virus species particularly relevant for infection and morbodity. Retroviruses and DNA viruses in comparison with oncogenic potentiality. Evaluation and importance of organic defenses, notably immune system responses, natural and adaptative immunity. Aspecific defense, defensines as well as antinfective peptides.
Robert F. Boyd - Microbiologia Generale- Medical Books Eds. Michael T.Madigan,John M.Martinko,Jack Parker- Biologia dei Microrganismi- Casa Editrice Ambrosiana G.B.Pier,J.B.Lyczak,L.M.Wetzler- Immunologia,Infezione,Immunita'-Piccin Ed.