GENERAL PATHOLOGY I
ACADEMIC YEAR: 2013/2014
YEAR OF STUDY: 2
SEMESTER: First semester
NUMBER OF CREDITS: 2
CONTACT HOURS: 16
INDIVIDUAL WORK HOURS: 36
The objectives of the General Pathology I course are to enable the acquisition of knowledge and understanding the mechanism of proliferation and cell death and their alteration in the biology of tumours, the pathogenesis of some human genetic and metabolic diseases with their related essential notions of semeiotic and medical terminology and mechanisms and alterations of the innate and adaptive immune response. The course allows the student to apply the knowledge gained in the context of biomedical laboratory.
General alteration of growth and death, cellular and molecular oncology with particular emphasis on tumour diagnosis in the laboratory practise. Genetic and metabolic diseases and general physiopathology.
Cellular alterations of growth and differentiation. Necrosis and apoptosis.
Definition, nomenclature, and biological properties of benign and malignant neoplasms. Molecular basis of cancer. Protooncogenes, oncogenes. Tumor suppressor genes. Diagnosis and biological basis of anti-neoplastic therapies.
Transmission patterns of single-gene disorders (Familial hypercholesterolemia, cystic fibrosis, sickle cell disease).
Atherosclerosis, trombosis, angina and myocardial infarction. Diabetes mellitus
Parola M. “Patologia Generale” EDISES
Pontieri G.M. “Elementi di Patologia Generale” III edizione PICCIN
The topics in the program will be presented and discussed through lectures trying to involve the student so that it can be an active part of the lesson.
Learning outcomes will be verified through an oral examination. Questions on the topics relating to the course will be used to test knowledge and understanding of the student in the scientific discipline, and her/his ability to apply such knowledge and understanding in occupational contexts. Using the knowledge also acquired in other courses the student must demonstrate knowledge and understanding about the etio-pathogenetic mechanisms of human diseases with their related essential notions of semeiotic and medical terminology.