GENERAL PATHOLOGY II
Learning outcomes of the course unit
The purpose of the course is to provide basic notions of Immunology, Immunopathology and Immunohematology, in particular the basis necessary for the application of the main immunological techniques.
Course contents summary
Blood and Hematopoiesis. Stem cells.
Innate immunity. Acquired immunity. The structural and functional aspects of Antibodies. T and B lymphocytes and their receptors. The Major Histocompatibility System (MHC). Activation of B and T lymphocytes. Vaccinations. Hypersensitivity. Immunologic tolerance and pathogenesis of autoimmune diseases. Transplantation. Immunodeficiency
General features of acute and chronic inflammation
Immunohematology ABO blood groups and serum antibodies. The rhesus (Rh) blood groups. Other blood groups. Haemolytic disease of the newborn.
Basic knowledge on the taking of a blood sample and fitness of donors.
Blood components and plasma by-products: properties, directions for use, preparation procedures and preservation.
Complications following blood transfusion and their handling.
Parola M. “Patologia Generale” EDISES
Pontieri G.M. “Elementi di Patologia Generale” III edizione PICCIN
Assessment methods and criteria