IMMUNOLOGY AND IMMUNOPATHOLOGY

The immune system (cells, primary and secondary lynphoid organs), lymphocytes recirculation
Acute inflammation: definition, aetiology, vascular and cellular changes, inflammatory cells and chemokynes, resultsa and consequences.
Chronic inflammation, primary and granulomatous: cellular aspects and mediators, systemic effects
Innate and acquired immunity
Antigens: structure and functions. Antigen-antibody link. Monoclonal antibodies.
B lynphocytes receptor and T lymphocytes receptor: Lymphocytes repertoire formation and clonal selection.
MHC I and II classes: structure and functions. Oesogenous and endocgenous antigen processing. Antigen presenting cells and organs transplantation.
Lymphocytes activation. Primary and secondary response. Immunological memory.
Laboratory methods based on antigen-antibody reactions and adaptative immunity cells.
Immunopathology princeples: hypersensitivities (I, II, III, IV). Tolerance and autoimmunity and pathogenetic mechanisms. Immunodeficiecies and immunodepression. Stress and immune system.