MORPHOLOGY AND GENETICS OF DEVELOPMENT
Learning outcomes of the course unit
the course means to supply the foundations of the developmental genetic and of the
organizations of the organism.
Course contents summary
Genes, genotype and phenotype. The chromosomes: structure and function.
Basic concepts of development: determination and differentiation, development patterns in Metazoa: the Drosophila.
Development of the body patterns: segmentation genes.
Determination of sex.
Genetic control of eye development and evolution of the eye and photoreceptors.
Suzuki DT, Griffiths AJF, Miller JH, Lewontin RC. Genetica. Principi di Analisi Formale. Zanichelli
Nusslein-volhard, C. and E. Wieschaus. 1980. Mutations affecting segment, number and polarity in Drosophila. Nature 287: 795-801
W.J. Gehring. (2005). New perspectives on eye development and the evolution of eyes and photoreceptors. Journal of Heredity 96:171-184
D. Arendt. (2003). Evolution of eyes and photoreceptor cell types. Int.J.Dev.Biol. 47:563-571
J. Chen and M. Fishman. (2000). Genetics of heart development. TIG 16:383-388
M. Simoes-Costa et al. (2005). The evolutionary origin of cardiac chambers. Dev.Biol. 277:1-15
W.J.Nelson. (2003). Tube morphogenesis: closure, but many openings remain. TCB 13:615-621
Assessment methods and criteria