Learning objectives
Acquisition of the basic knowledge about the principles that govern the interactions of drugs with the organism, both in terms of pharmacokinetics (absorption, metabolism, distribution and elimination) and pharmacodynamics (mechanism of action), the basics on the principles of general toxicology , adverse reactions of drugs and their evaluation, the knowledge of the fundamental aspects associated with the therapeutic use of some drugs more specific interest, with potential ototoxic effects.
Prerequisites
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Course unit content
Introduction: general principles.
Pharmacokinetics: the dynamics of drug absorption, distribution, metabolism, and elimination.
Pharmacodynamics. Molecular mechanisms of drug action. Relationship between drug concentration and effect. Relationship between drug dose and clinical response: factors that modify the drug response.
Toxicology: general principles, dose-response relationship, classification of undesirable effects.
Drugs with potential ototoxic effects.
Full programme
Introduction: general principles.
Pharmacokinetics: the dynamics of drug absorption, distribution, metabolism and elimination.
Pharmacodynamics. Molecular mechanisms of drug action. Relationship between drug concentration and effect. Relationship between drug dose and clinical response: factors that modify the drug response.
Toxicology: general principles, dose-response relationship, classification of undesirable effects.
Drugs with potential ototoxic effects.
Bibliography
Rang H.P., Dale M.M., Ritter J.M., Moore P.K.: Farmacologia. Casa Editrice Ambrosiana, last edition
Dale M.M., Haylett D.G.: Elementi di farmacologia. Compendio per l’esame. EMSI, last edition
Lüllmann H., Mohr K.: Farmacologia per immagini. Atlante tascabile. Centro Scientifico Editore, last edition
Teaching methods
Lectures
Assessment methods and criteria
Oral examination
Other information
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